Abnormal QT responses to adenosine in subjects with long QT syndrome: reply
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چکیده
منابع مشابه
Abnormal QT responses to adenosine in subjects with long-QT syndrome.
In the interesting article by Viskin et al., adenosine-induced bradycardia was found to produce a higher increase in QT and a lower decrease in QTc (calculated using the Bazett formula) in subjects with long-QT syndrome (LQTS) than in controls. However, a major issue in this study concerns the reliability of QT correction when large ranges of heart rates are analysed. The Bazett formula overcor...
متن کاملProvocation of sudden heart rate oscillation with adenosine exposes abnormal QT responses in patients with long QT syndrome: a bedside test for diagnosing long QT syndrome.
AIMS As arrhythmias in the long QT syndrome (LQTS) are triggered by heart rate deceleration or acceleration, we speculated that the sudden bradycardia and subsequent tachycardia that follow adenosine injection would unravel QT changes of diagnostic value in patients with LQTS. METHODS AND RESULTS Patients (18 LQTS and 20 controls) received intravenous adenosine during sinus rhythm. Adenosine ...
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Introduction: Long QT syndrome (LQTS) is a type of ventricular arrhythmia characterized by prolonged QT intervals on electrocardiogram or delay in ventricular repolarization and it can lead to syncope, seizure and sudden cardiac death. Here, KCNE1 and KCNE2 variants are studied among Iranian affected families with this syndrome. Materials and Methods: Fifty patients referring to Rajaei Cardiov...
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BACKGROUND The rate-corrected QT interval (QTc) is heritable, and the discovery of quantitative trait loci that influence the QTc would be an important step in identifying the genes responsible for life-threatening arrhythmias in the general population. We studied 66 pairs of unselected normal dizygotic (DZ) twin subjects and their parents in a sib-pair analysis. We tested for linkage of gene l...
متن کاملThe Long QT Syndrome
Introduction The Long QT syndrome (LQTS) can be inherited or acquired and is of particular interest and concern at present. Patients with LQTS are predisposed to the ventricular tachyarrhythmia torsade de pointes (TdP) which causes syncope and sudden death. Inherited LQTS is the prototype of the "primary cardiac arrhythmias" or "cardiac ion channelopathies". The study of inherited LQTS has prov...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2006
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehl074